Machine Learning-Driven Discovery of STAT3 as a Pivotal Target for Wen-Wei-San-Ji Formula in Chronic Atrophic Gastritis Therapy: Multi-Omics Integration and Experimental Confirmation

This study indicated that WWSJ can inhibit the expression of STAT3 and p-STAT3(Tyr 705) proteins, suggesting that WWSJ may suppress the JAK-STAT3 signaling pathway.