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circZFR promote lung carcinogenesis and oxidative phosphorylation by modulating alternative splicing

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NIAID Data Ecosystem2026-05-01 收录
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Our study suggested that circZFR was a potential oncogene in lung adenocarcinoma. To investigate the function of circZFR, we performed high-thoughput RNA sequencing (RNA-Seq) assays after the silence of circZFR in A549 cell lines. Overall design: In human lung adenocarcinoma A549 cells, we downregulated the expression of circZFR utilizing small interference RNA (siRNA) and used scrumble as negative control. Then we used RNA-Seq to reveal the change of mRNA profiles after the silence of circZFR.

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2023-09-13
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