ENAH EVH1 in complex with Ac-WPPPPTEDEL-NH2

ENAH EVH1 in complex with Ac-WPPPPTEDEL-NH2 Descriptor: ActA-derived 10-mer Ac-FPPPPTEDEL-NH2 with acetylated (Ac) and amidated (NH2) termini. Phe is substitued by Trp to increase affinity for crystallization, Protein enabled homolog Authors: Barone, M, Roske, Y. Deposit date: 2017-03-03 Release date: 2018-03-21 Last modified: 2024-11-13 Method: X-RAY DIFFRACTION (2.7 Å) Cite: Designed nanomolar small-molecule inhibitors of Ena/VASP EVH1 interaction impair invasion and extravasation of breast cancer cells. Proc.Natl.Acad.Sci.USA, 117, 2020