Stem Cell Antigen-1 (Sca-1) Regulates Mammary Tumor Development and Cell Migration

ChEBI2012-02-16 更新2026-07-21 收录

肿瘤发生机制

细胞迁移调控

数据链接：

https://www.ebi.ac.uk/biostudies/ArrayExpress/studies/E-GEOD-30684 数据链接链接失效反馈

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资源简介：

Stem Cell Antigen-1 (Sca-1) Regulates Mammary Tumor Development and Cell Migration

创建时间：

2012-02-16

Cellular crowd control: overriding endogenous cell coordination makes cell migration more susceptible to external programming

细胞迁移调控

生物编程

The uploaded files include 1) raw data used to generate plots and graphs included in the manuscript, 2) the total raw dataset from all experiments, 3) representative raw videos per experimental condit

NIAID Data Ecosystem80

Transcriptome changes following loss of Apc in the intestine. Mus musculus

肿瘤发生机制

Wnt信号通路靶基因

Nearly all colorectal cancers have dysregulated Wnt signalling, predominantly through the mutation of the Apc (Adenomatous Polyposis Coli) gene. Therefore it is of vital importance to elucidate the ke

NIAID Data Ecosystem40

OncoSig: a new algorithm for the accurate and systematic de novo prediction of Oncoprotein-centric Signaling networks. OncoSig: a new algorithm for the accurate and systematic de novo prediction of Oncoprotein-centric Signaling networks

癌症信号网络

肿瘤发生机制

We introduce a new algorithm, OncoSig, to address the deficiencies of canonical pathways through the accurate, context-specific prediction of proteins representing both known and novel functional memb

NIAID Data Ecosystem30

p53 amyloid formation induced cellular transformation and tumor formation in xenograft model

p53

肿瘤发生机制

p53 mutation and its subsequent loss of function along with gain of oncogenic functions is associated with cancer. However, the exact mechanism of how altered p53 acts as an oncogene is not clear yet.

NIAID Data Ecosystem50

Figure S1 - Tyrosine Y189 in the Substrate Domain of the Adhesion Docking Protein NEDD9 Is Conserved with p130Cas Y253 and Regulates NEDD9-Mediated Migration and Focal Adhesion Dynamics

蛋白质序列比对

细胞迁移调控

Cas family proteins sequence alignment. Sequences aligned at the PRALINE website. (PDF)

Figshare2015-12-02 更新40