scRNA-seq analysis of hydrosalphinx disease state Vs healthy state of human fallopian tubes

Hydrosalpinx is common cause of tubal factor infertility in women in which the fallopian tube becomes blocked, fills with fluid, and consequently is nonfunctional. Single cell RNA-seq analysis has provided an unparalleled approach to characterize tissue types and explore pathologies in unbiased manner. Here we use scRNA-seq to define and compare major and rare cell types of the human fallopian tube in the healthy and hydrosalpinx disease state. Overall design: Characterizing cellular composition and heterogeneity of healthy state and hydrosalpinx disease state of the human fallopian tubes using 10x scRNA-seq analysis