siRNA knockdown of neonatal rat cardiac myocytes and fibroblasts

Alliance of Genome Resources2026-08-01 收录

心脏细胞siRNA敲低

Yap基因功能

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https://www.ncbi.nlm.nih.gov/gds/?term=GSE112464 数据链接链接失效反馈

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Primary neonatal rat cardiac myocytes or fibroblasts were isolated and subjected to siRNA mediated Yap knockdown

Cardiac-specific YAP activation improve cardiac function and survival in an experimental murine MI model

心肌梗死基因治疗

Yap基因功能

In this study, we used a cardiac-specific, inducible expression system to activate YAP in adult mouse heart. Activation of YAP in adult heart promoted cardiomyocyte proliferation and did not deleterio

NIAID Data Ecosystem40

Identification of Yap-interacting proteins in Xenopus egg extracts by co-immunoprecipitation coupled to LC/MS/MS

DNA复制调控

Yap基因功能

Yap (Yes-associated protein 1) is a downstream effector of the Hippo signaling pathway and known as a transcriptional co-activator. We previously identified Yap1 as a novel factor implicated in the co

NIAID Data Ecosystem30

Expression profile of mouse embryonic stem cells upon knockdown or overexpression of YAP

干细胞基因调控

Yap基因功能

We looked at the expression profiles of embyonic stem cells (ESCs) 48 hours after YAP siRNAs transfection, to knockdown YAP expression, or after pCAG-YAP transfection, to over-express YAP protein. To

NIAID Data Ecosystem20

Activated YAP1 stimulates cardiomyocyte proliferation. Rattus norvegicus

心肌细胞增殖

Yap基因功能

Postnatal day 4 neonatal rat cardiomyocytes transduced with LacZ or flag-tagged, activated YAP1 (S127A) expressing adenovirus After transduction, cells were cultured in serum free media and collected

NIAID Data Ecosystem30

Hepatic Stellate Cells inhibition induced by YAP deletion

纤维化机制

Yap基因功能

Gene expression by bulk RNAseq in isolated mouse Hepatic Stellate Cells (HSC) YAP ko compared to HSC YAP floxed (wt). Overall design: Bullk RNA sequencing was used to characterize gene expression of p

NIAID Data Ecosystem20

siRNA knockdown of neonatal rat cardiac myocytes and fibroblasts

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