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A new landscape for malaria vaccine development
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2024-06-27
相关数据集
Plasmodium falciparum Erythrocyte Membrane Protein 1 Diversity in Seven Genomes – Divide and Conquer
The var gene encoded hyper-variable Plasmodium falciparum erythrocyte membrane protein 1 (PfEMP1) family mediates cytoadhesion of infected erythrocytes to human endothelium. Antibodies blocking cytoad
NIAID Data Ecosystem60
Phase 1 Trial With Challenge to Assess the Safety and Biomarkers of Protection in Malaria-naive Adults of Immunization Via Mosquito Bite With Radiation-Attenuated Plasmodium Falciparum Sporozoites (IMRAS) - Day 140-147. Phase 1 Trial With Challenge to Assess the Safety and Biomarkers of Protection in Malaria-naive Adults of Immunization Via Mosquito Bite With Radiation-Attenuated Plasmodium Falciparum Sporozoites (IMRAS) - Day 140-147
This study is to assess the safety, tolerability, and biomarkers of protection in healthy malaria-naive adults, who will receive bites from Anopheles stephensi mosquitoes either infected with Plasmodi
NIAID Data Ecosystem20
First field efficacy trial of the ChAd63 MVA ME-TRAP vectored malaria vaccine candidate in 5-17 months old infants and children
Background Heterologous prime boost immunization with chimpanzee adenovirus 63 (ChAd63) and Modified Vaccinia Virus Ankara (MVA) vectored vaccines is a strategy previously shown to provide substantial
NIAID Data Ecosystem10
Summary of Parasitemia Data in Experiment #1
‘Day 1st parasitemia’ is the day after sporozoite challenge when parasites were first seen on malaria smear. ‘Day >1% parasitemia’ is the day of drug treatment (‘unknown’ means that monkeys were drug
Figshare2015-12-02 更新30
Safety, immunogenicity, and efficacy of the IV PfSPZ Vac in Tanzania (BSPZV1). Safety, immunogenicity, and efficacy of the IV PfSPZ Vac in Tanzania (BSPZV1)
This trial will evaluate whether relatively non-immune populations in endemic countries can effectively generate significant cellular and humoral immune responses that confer protection against P. fal
NIAID Data Ecosystem20
