Gut Mycobiota Dysbiosis in People living with HIV/AIDS with Severe Immunosuppression: insights from an Argentine cohort

Intestinal dysbiosis is common in people living with HIV-AIDS (PLWH), yet fungal communities (mycobiota) remain poorly characterized, especially in severely immunosuppressed patients. This study provides novel insights into gut mycobiota in severely immunosuppressed PLWH in Argentina, highlighting Candida-dominated dysbiosis linked to chronic diarrhea and antibiotic exposure, and revealing the regional prevalence of Histoplasma capsulatum as a component of the gut mycobiota.