Hepatic IRG1 promotes apoptosis and hepatocarcinogenesis by trapping Mcl-1

NIAID Data Ecosystem2026-03-13 收录

肝细胞癌病因

细胞凋亡调控

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Raw data for "Hepatic IRG1 promotes apoptosis and hepatocarcinogenesis by trapping Mcl-1"

创建时间：

2022-06-30

CRYSTAL STRUCTURE OF THE XIAP/CASPASE-7 COMPLEX

细胞凋亡调控

蛋白质结构解析

CRYSTAL STRUCTURE OF THE XIAP/CASPASE-7 COMPLEX Descriptor: BACULOVIRAL IAP REPEAT-CONTAINING PROTEIN 4, CASPASE-7 Authors: Huang, Y, Park, Y.C, Rich, R.L, Segal, D, Myszka, D.G, Wu, H. Deposit date:

Protein Data Bank Japan2023-08-09 更新60

Yap1 safeguards mouse embryonic stem cells from excessive apoptosis during differentiation

胚胎干细胞分化

细胞凋亡调控

While Yap1, a Hippo pathway transcriptional effector, plays numerous roles in development and cancer, its functions in embryonic stem (ES) cell differentiation remain poorly characterized. It is known

NIAID Data Ecosystem40

A maternal high-fat diet induces fetal origins of NASH-HCC in mice

非酒精性脂肪性肝病机制

肝细胞癌病因

Maternal overnutrition affects offspring susceptibility to nonalcoholic steatohepatitis (NASH). Male offspring from high-fat diet (HFD)-fed dams developed a severe form of NASH, leading to highly vasc

NIAID Data Ecosystem30

Midnolin Regulates Liver Cancer Cell Growth In Vitro and In Vivo. Midnolin Regulates Liver Cancer Cell Growth In Vitro and In Vivo

肝细胞癌病因

基因功能研究

Hepatocellular carcinoma (HCC) ranks worldwide as one of the most lethal cancers. In spite of the vast existing knowledge about HCC, the pathogenesis of HCC is not completely understood. Discovery of

NIAID Data Ecosystem50

Supplementary Dataset1 and 2

N端乙酰化

细胞凋亡调控

N-terminal acetyltransferase B (NatB) is a major contributor to the N-terminal acetylome and is implicated in several key cellular processes including apoptosis and proteostasis. However, the molecula

Figshare2024-07-10 更新40

Hepatic IRG1 promotes apoptosis and hepatocarcinogenesis by trapping Mcl-1

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