Differential gene expression following paclitaxel treatment of iPSC-dSN.

NIAID Data Ecosystem2026-03-13 收录

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https://figshare.com/articles/dataset/Differential_gene_expression_following_paclitaxel_treatment_of_iPSC-dSN_/17908502 数据链接链接失效反馈

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资源简介：

Comparison between paclitaxel and vehicle treatment of iPSC-dSN in clusters 2, 7, and 8 (FDR<0.05).

创建时间：

2022-01-05

RNAseq highlights the role of Sirt2 in protecting neuronal cell from cisplatin-treated injury. RNAseq highlights the role of Sirt2 in protecting neuronal cell from cisplatin-treated injury

化疗神经毒性

神经保护作用

Background: Cisplatin is a common and effective chemotherapeutic agent used to treat various cancers. However, it has a dose-limiting effect, resulting in chemotherapy-induced peripheral neuropathy (C

NIAID Data Ecosystem70

Activation of a nerve injury transcriptional signature in airway-innervating sensory neurons after lipopolysaccharide induced lung inflammation I

神经炎症反应

感觉神经元转录组学

While the inflammatory immune response of the lung to allergens and pathogens has been extensively studied, little is known about how sensory nerves change in response to an inflammatory insult within

NIAID Data Ecosystem50

Nppb Neurons Are Sensors Of Mast Cell-Induced Itch

瘙痒神经机制

感觉神经元转录组学

Itch is an unpleasant skin sensation which can be triggered by exposure to many chemicals including those released by mast cells. The Nppb-expressing class of sensory neurons when activated elicit scr

NIAID Data Ecosystem30

Gene expression signatures of chemotherapy-induced neuropathy induced by cisplatin and oxaliplatin. Gene expression signatures of chemotherapy-induced neuropathy induced by cisplatin and oxaliplatin

化疗神经毒性

转录组生物标志物

Vincristine, oxaliplatin, and cisplatin are commonly prescribed chemotherapeutic agents for the treatment of several cancer types. However, a main side-effect is chemotherapy-induced peripheral neurop

NIAID Data Ecosystem60

Optimal outcome measures for assessing exercise and rehabilitation approaches in chemotherapy-induced peripheral-neurotoxicity: Systematic review and consensus expert opinion

化疗神经毒性

康复干预

Chemotherapy-induced peripheral neurotoxicity (CIPN) remains a significant toxicity in cancer survivors without preventative strategies or rehabilitation. Exercise and physical activity-based interven

DataCite Commons2022-01-31 更新40

Differential gene expression following paclitaxel treatment of iPSC-dSN.

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