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2020-03-18
相关数据集
Additional file 9: of NmeCas9 is an intrinsically high-fidelity genome-editing platform
Table S7. Primer sequences used for on- and off-target deep sequencing analysis for all genomic editing sites analyzed by GUIDE-seq. (XLSX 28 kb)
Figshare2024-02-08 更新80
Metabolic effects of an aspartate aminotransferase-inhibitor on two T-cell lines
An emerging method to help elucidate the mode of action of experimental drugs is to use untargeted metabolomics of cell-systems. The interpretations of such screens are however complex and more exampl
NIAID Data Ecosystem30
Binding site volumes and normalized docking scores (NDS) of CETP inhibitors for CETP and six classes of putative off-targets.
The predicted binding affinities are grouped with different symbols: * represents strong binding affinity (NDS NDS>−2.0), and others represent less likely binding due to
NIAID Data Ecosystem20
Gene replacement of alpha-globin with beta-globin restores hemoglobin balance in beta-thalassemia-derived hematopoietic stem and progenitor cells
Targeted deep sequencing of top-40 predicted off-target sites for HBA1-specific 3' UTR guide RNA reported in Cromer, et al., Nature Medicine, 2021.
NIAID Data Ecosystem50
