Replication of the 40 top hits of the TwinsUK discovery sample (using the discordant MZ subsample and the full unrelated twin invidiual sample) in the KORA sample (n = 1485).
Probability of successful replication based on “pooling” initial and follow-up data sets, when following up on SNPs selected for moderate or high association signals.
To be included in this table, we require a two-tailed P≤0.05 after Bonferroni correction for the number of independent loci reported in the NHGRI database (Table S5). We report the association results
We tested the novel associations in the UK Biobank discovered by PAT and HIPO for replication in the GIANT consortium. We separately clumped using the lead variant as determined by the m-value. For ea
