Crystal structure of human cGAS apo form Descriptor: Cyclic GMP-AMP synthase, ZINC ION Authors: Kato, K, Ishii, R, Ishitani, R, Nureki, O. Deposit date: 2013-09-05 Release date: 2013-10-30 Last modifi
Gp130 dependent gene expression was analyzed in a previously established hepatocyte-specific gp130-knockout mouse model. Whole transcriptome analysis for isolated hepatocytes was performed to measure
IRF3 translocates from the cytoplasm to the nucleus upon recognition of a cytoplasmic RNA stimulus by RIG-I or MDA5. Using an optical pooled CRISPR knockout screen in HeLa-Cas9 cells, we identified AT
Background: Asthma is the most common chronic lung disorder among children and young adults worldwide. Standard of care therapies are only partially effective and have side effects. Despite highly ef