Raw image files for study. The β2-adrenergic receptor (β2AR), a prototypic G protein-coupled receptor (GPCR), is a powerful driver of bronchorelaxation, but the effectiveness of β-agonist drugs in ast
VIP and PACAP are pleiotropic peptides belonging to the secretin superfamily of brain-gut peptides and interact specifically with three receptors (VPAC1, PAC1 and VPAC2) from the class II B G protein-
G protein coupled receptor (GPCR) signalling covers three major mechanisms. GPCR agonist engagement allows for the G proteins to bind to the receptor leading to a classical downstream signalling casca
Additional file 5: Table S5. Nodes and edges for the causal map of vasopressin effects in IMCD. Source nodes were mapped to Target nodes based on literature searches and data from this paper. Informat