G protein coupled receptor (GPCR) signalling covers three major mechanisms. GPCR agonist engagement allows for the G proteins to bind to the receptor leading to a classical downstream signalling casca
A complex structure of arrestin-2 bound to neurotensin receptor 1 Descriptor: Beta-arrestin-1, Fab30 heavy chain, Fab30 light chain, ... Authors: Yin, W, Li, Z, Jin, M, Yin, Y.-L, de Waal, P.W, Pal, K
Additional file 5: Table S5. Nodes and edges for the causal map of vasopressin effects in IMCD. Source nodes were mapped to Target nodes based on literature searches and data from this paper. Informat
Activation of Gα(i)-coupled receptors often causes enhancement of the inositol phosphate signal triggered by Gα(q)-coupled receptors. To investigate the mechanism of this synergistic receptor crosstal
