Crystal structure of p38 kinase bound to pyrimido-pyridazinone inhibitor
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Crystal structure of p38 kinase bound to pyrimido-pyridazinone inhibitor Descriptor: 5-(2,6-dichlorophenyl)-2-[(2,4-difluorophenyl)sulfanyl]-6H-pyrimido[1,6-b]pyridazin-6-one, CHLORIDE ION, Mitogen-activated protein kinase 14 Authors: Jacobs, M.D, Bellon, S. Deposit date: 2008-11-20 Release date: 2008-12-09 Last modified: 2023-12-27 Method: X-RAY DIFFRACTION (2.4 Å) Cite: Evaluating the molecular mechanics poisson-boltzmann surface area free energy method using a congeneric series of ligands to p38 MAP kinase. J.Med.Chem., 48, 2005
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2008-11-20
