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In vitro and in vivo characterization of a novel, highly potent p53-MDM2 inhibitor

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Protein Data Bank Japan2024-01-17 更新2026-03-21 收录
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https://pdbj.org/mine/summary/6ggn
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In vitro and in vivo characterization of a novel, highly potent p53-MDM2 inhibitor Descriptor: (4~{S})-4-(4-chloranyl-2-methyl-phenyl)-5-(5-chloranyl-2-methyl-phenyl)-2-(2,4-dimethoxypyrimidin-5-yl)-3-propan-2-yl-4~{H}-pyrrolo[3,4-d]imidazol-6-one, CHLORIDE ION, E3 ubiquitin-protein ligase Mdm2 Authors: Kallen, J. Deposit date: 2018-05-03 Release date: 2018-09-26 Last modified: 2024-01-17 Method: X-RAY DIFFRACTION (2 Å) Cite: In vitro and in vivo characterization of a novel, highly potent p53-MDM2 inhibitor. Bioorg. Med. Chem. Lett., 28, 2018
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2018-05-03
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