MM/PBSA binding free energies (kJ/mol) of wild-type and mutant AIRE-PHD1/H3K4me0 complexes.

1experimental binding free energy as measured in [15], [20].2difference between wild-type and mutant experimental binding free energies.3computational binding free energies.4difference between computational binding free energies of wild-type and mutant complex.5coulombic term.6polar solvation term.7polar term (sum of coulombic and polar solvation terms).8van der Waals term.9non-polar solvation term.10non-polar term (sum of van der Waals and non polar solvation terms).Standard errors are given in parentheses.

1. 实验性结合自由能，如[15]、[20]中所测得。2. 野生型与突变型实验性结合自由能之间的差异。3. 计算性结合自由能。4. 野生型与突变型复合物计算性结合自由能之间的差异。5. 库仑项。6. 极性溶剂化项。7. 极性项（库仑项与极性溶剂化项之和）。8. 范德华项。9. 非极性溶剂化项。10. 非极性项（范德华项与非极性溶剂化项之和）。标准误差以括号内给出。