Crystal structure of HCV NS5B polymerase with a novel pyridazinone inhibitor
收藏Protein Data Bank Japan2024-04-03 更新2026-03-21 收录
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Crystal structure of HCV NS5B polymerase with a novel pyridazinone inhibitor Descriptor: N-{3-[4-hydroxy-1-(3-methylbutyl)-2-oxo-1,2-dihydropyrrolo[1,2-b]pyridazin-3-yl]-1,1-dioxido-2H-1,2,4-benzothiadiazin-7 -yl}methanesulfonamide, RNA-directed RNA polymerase Authors: Han, Q, Showalter, R.E, Zhao, Q, Kissinger, C.R. Deposit date: 2008-03-27 Release date: 2009-02-10 Last modified: 2024-04-03 Method: X-RAY DIFFRACTION (2.1 Å) Cite: Pyrrolo[1,2-b]pyridazin-2-ones as potent inhibitors of HCV NS5B polymerase. Bioorg.Med.Chem.Lett., 18, 2008
创建时间:
2008-03-27



