The accessory protein Orf6 is uniquely expressed in sarbecoviruses including severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) which is an ongoing pandemic. SARS-CoV-2 Orf6 antagonizes host

NIAID Data Ecosystem10

Structural, biochemical and functional characterization of the essential host factor SETD3 in complex with the enterovirus CV-B3 2A protease

病毒-宿主蛋白互作结构解析

抗肠道病毒药物靶点

Enteroviruses cause a number of medically relevant and widespread human diseases with no approved antiviral therapies currently available. We have previously identified the actin histidine methyltrans

NIAID Data Ecosystem10

Tandem chromodomains of human CHD1 in complex with influenza NS1 C-terminal tail dimethylated at K229

组蛋白模拟机制

病毒-宿主蛋白互作结构解析

Tandem chromodomains of human CHD1 in complex with influenza NS1 C-terminal tail dimethylated at K229 Descriptor: Chromodomain-helicase-DNA-binding protein 1, GLYCEROL, Nonstructural protein 1, ... Au

Protein Data Bank Japan2023-09-20 更新30

Crystal structure of SARS-CoV-2 receptor-binding domain complexed with squirrel ACE2

病毒-宿主蛋白互作结构解析

跨物种ACE2识别机制

Crystal structure of SARS-CoV-2 receptor-binding domain complexed with squirrel ACE2 Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-

Protein Data Bank Japan2025-10-15 更新10

Crystal structure of the c-Src SH3 domain in complex with a peptide from the Hepatitis C virus NS5A-protein

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