Data for: Evaluating the feasibility of applying Cobalt-Hydroxyapatite ingots to radiotherapy markers

Substitution of cobalt for calcium in hydroxyapatite resulted in CoHA with a higher effective atomic number. This study evaluated various medical imaging characteristics of round CoHA ingots in porcine phantom to demonstrate the feasibility of using CoHA ingots as a radiotherapy marker. CoHA was compressed into round ingots and then implanted into phantom of porcine liver and gelatin phantom of porcine vertebra along with three commercially available radiotherapy markers. The phantom were scanned and photographed using a routine x-ray imager, magnetic resonance imager, computed tomography (CT) imager, and ultrasound imager, respectively, followed by image analysis in ImageJ software. CoHA ingots could be clearly identified with general imaging instruments (X-ray, CT, and ultrasound) and the image size did not change. There were some metal artifacts in the magnetic resonance images. CoHA ingots can be used with most medical imaging instruments to help quickly identify the location and extent of soft-tissue tumors, and are biodegradable, that is, they can be self-absorbed by the body over time to avoid interference with follow-up disease screening

以钴取代羟基磷灰石中的钙元素，从而制得具有更高有效原子序数的CoHA。本研究评估了猪体模型中圆形CoHA锭的多种医学影像特性，以验证CoHA锭作为放疗标志物的可行性。将CoHA压缩成圆形锭，并植入猪肝模型及猪脊椎的明胶模型中，同时植入三种市售放疗标志物。分别使用常规X射线成像仪、磁共振成像仪、计算机断层扫描（CT）成像仪和超声成像仪对模型进行扫描和拍照，随后在ImageJ软件中进行图像分析。CoHA锭可通过常规成像仪器（X射线、CT和超声）清晰识别，且图像尺寸未发生变化。在磁共振图像中存在一些金属伪影。CoHA锭可与大多数医学成像仪器配合使用，有助于快速识别软组织肿瘤的位置和范围，且具有生物可降解性，即它们可以随着时间的推移被身体自行吸收，从而避免干扰后续的疾病筛查。