Changes of Intestinal Microbiota and Liver Metabolomics in Yellow Catfish (Pelteobagrus fulvidraco) Before and After Rice Flowering in Rice-fish symbiosis farmed mode (RFFM) (PRJCA043453)

This study analyzed the intestinal microbiota and liver metabolomics in yellow catfish (Pelteobagrus fulvidraco) before and after rice flowering in rice-fish symbiosis farmed mode (RFFM). our study demonstrates that in the rice-fish symbiosis farming model (RFFM), the gut microbiota of yellow catfish improved significantly after rice flowering. The dominant bacterial genera in the gut microbiota after-flowering were Brevundimonas, Oxyphotobacteria_unclassified, and Clostridium_sensu_stricto_1. Hepatic metabolism also underwent substantial changes, with lipid metabolism downregulated and amino acid metabolism upregulated, likely as an adaptive response to environmental shifts in the rice paddy ecosystem. Notably, Clostridium_sensu_stricto_1 played a key role in mediating hepatic metabolic adjustments, highlighting its potential influence on metabolic regulation in yellow catfish under the RFFM. These findings provide new insights into the development of host-derived probiotics for aquaculture.