Impact of Mbd3/NuRD on gene expression and chromatin accessibility in early haematopoiesis
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To determine the impact of the Mbd3/NuRD chromatin remodelling complex on haematopoietic differentiation, we generated mice that lack Mbd3/NuRD in haematopoiesis. We then measured gene expression in haematopoietic stem cells and early lymphoid progenitor cells by RNA-seq, and chromatin accessibility by ATAC-seq.
创建时间：
2017-09-30
