GWAS summary statistics for genetically informed cortical phenotypes

#Summary statistics from GWAS analyses of 24 genetically informed cortical phenotypes#Including two global measures: total cortical surface area, mean cortical thickness########################################Sample size n=36289 (UK Biobank White-British cohort) Number of reported SNPs: ~15178763 (Chromosomes 1-22) ########################################GWAS was performed with fastGWA, using a sparse GRM as input as implemented in GCTA: https://cnsgenomics.com/software/gcta/index.html#fastGWA/ Each file contains the following columns: #CHR Chromosome#SNP SNP identifier#POS Base-pair position#A1 Effect allele (minor allele by default) #A2 Other allele#N Sample size#AF1 Frequency of A1#BETA SNP effect#SE SNP standard error#P p-value ######################################## #The dataset comprises GWAS summary statistics for 50 brain MRI phenotypes: 12 regional measures of cortical surface area and 12 of cortical thickness, each with a version adjusted for the corresponding global measure. It also includes two global measures: total cortical surface area and mean cortical thickness. #All brain phenotypes were pre-residualized prior to GWAS to remove the effects of age, sex, scanner, and the top 10 genetic principal components. #Full summary statistics file names UKB_36k_motor_premoter_area_global_adjusted.gzUKB_36k_motor_premoter_area_no_global_adjustment.gzUKB_36k_occipital_area_global_adjusted.gzUKB_36k_occipital_area_no_global_adjustment.gzUKB_36k_posterolateral_temporal_area_global_adjusted.gzUKB_36k_posterolateral_temporal_area_no_global_adjustment.gzUKB_36k_superior_parietal_area_global_adjusted.gzUKB_36k_superior_parietal_area_no_global_adjustment.gzUKB_36k_orbitalfrontal_area_global_adjusted.gzUKB_36k_orbitalfrontal_area_no_global_adjustment.gzUKB_36k_superior_temporal_area_global_adjusted.gzUKB_36k_superior_temporal_area_no_global_adjustment.gzUKB_36k_inferior_parietal_area_global_adjusted.gzUKB_36k_inferior_parietal_area_no_global_adjustment.gzUKB_36k_dorsomedial_frontal_area_global_adjusted.gzUKB_36k_dorsomedial_frontal_area_no_global_adjustment.gzUKB_36k_anteromedial_temporal_area_global_adjusted.gzUKB_36k_anteromedial_temporal_area_no_global_adjustment.gzUKB_36k_precuneus_area_global_adjusted.gzUKB_36k_precuneus_area_no_global_adjustment.gzUKB_36k_dorsolateral_prefrontal_area_global_adjusted.gzUKB_36k_dorsolateral_prefrontal_area_no_global_adjustment.gzUKB_36k_pars_opercularis_area_global_adjusted.gzUKB_36k_pars_opercularis_area_no_global_adjustment.gzUKB_36k_motor_premoter_SMA_thickness_global_adjusted.gzUKB_36k_motor_premoter_SMA_thickness_no_global_adjustment.gzUKB_36k_superior_perietal_thickness_global_adjusted.gzUKB_36k_superior_perietal_thickness_no_global_adjustment.gzUKB_36k_inferior_parietal_thickness_global_adjusted.gzUKB_36k_inferior_parietal_thickness_no_global_adjustment.gzUKB_36k_perisylvian_thickness_global_adjusted.gzUKB_36k_perisylvian_thickness_no_global_adjustment.gzUKB_36k_occipital_thickness_global_adjusted.gzUKB_36k_occipital_thickness_no_global_adjustment.gzUKB_36k_ventromedial_occipital_thickness_global_adjusted.gzUKB_36k_ventromedial_occipital_thickness_no_global_adjustment.gzUKB_36k_ventral_frontal_thickness_global_adjusted.gzUKB_36k_ventral_frontal_thickness_no_global_adjustment.gzUKB_36k_temporal_pole_thickness_global_adjusted.gzUKB_36k_temporal_pole_thickness_no_global_adjustment.gzUKB_36k_medial_temporal_thickness_global_adjusted.gzUKB_36k_medial_temporal_thickness_no_global_adjustment.gzUKB_36k_middle_temporal_thickness_global_adjusted.gzUKB_36k_middle_temporal_thickness_no_global_adjustment.gzUKB_36k_dorsolateral_prefrontal_thickness_global_adjusted.gzUKB_36k_dorsolateral_prefrontal_thickness_no_global_adjustment.gzUKB_36k_medial_prefrontal_thickness_global_adjusted.gzUKB_36k_medial_prefrontal_thickness_no_global_adjustment.gzUKB_36k_total_surface_area.gzUKB_36k_mean_cortical_thickness.gz