SUMOylation of CREBBP with SUMO1
收藏reactome.org2025-03-25 收录
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As inferred from mouse homologs, CREBBP (CBP) is SUMOylated at lysine-998, lysine-1033, and lysine-1056 with SUMO1. SUMOylation recruits DAXX and HDAC2 to repress transcription.
根据对小鼠同源基因的推断，CREBBP（CBP）在赖氨酸-998、赖氨酸-1033和赖氨酸-1056处被SUMO1进行SUMO化修饰。SUMO化修饰过程可募集DAXX和HDAC2蛋白，从而抑制转录。
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