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Differential RNA expression profiling in response to TET inhbition

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NIAID Data Ecosystem2026-04-25 收录
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Ten-to-Eleven Translocation (TET) family of proteins oxidize 5mC in to 5hmC on the genomic DNA and act as interesting class of epigenetic medulators. A novel small molecule inhbitor of TET enzymatic activity, C35 is developed. Overall design: Mouse Embryonic Fibroblasts are treated with C35 for 7 days and total mRNA sequecning is performed.

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2020-01-01
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