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Formal [4+1] Annulation of Cyclopropyl Amides and Water Mediated by Lewis Acid: A Novel Entry to γ-Butyrolactones

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http://www.thieme-connect.com/DOI/DOI?10.1055/s-0031-1290971
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资源简介:
An efficient one-pot synthesis of substituted γ-butyrolactones from cyclopropyl amides mediated by the Lewis acid SnCl4·5H2O is reported. A mechanism involving a tandem ring-opening reaction and intramolecular cyclization reaction is proposed.
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© Georg Thieme Verlag
创建时间:
2012-06-04
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