NMR titration experiments that study binding of a NIR emitting osmium polypyridyl probe to cMYC and hTel G-quadruplex DNA
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1D and 2D NMR spectra of cMYC and hTel G-quadruplex DNA and their complexes with Λ-<strong> </strong>and Δ<strong>-</strong>enantiomers of the osmium polypyridyl probe [Os(TAP)<sub>2</sub>(dppz)]<sup>2+</sup>. Spectra were recorded on a 600 MHz NMR spectrometer with 70 mM KCl, 20 or 25 mM K-phosphate buffer, pH 7, 298 K, in 90% H<sub>2</sub>O and 10% D<sub>2</sub>O at 25 °C.
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2022-10-14
