Rhodium(III)-Catalyzed Addition of Indoles with Boc-Imines via C-H Bond Activation
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A rhodium-catalyzed alkylation reaction of indoles with N-Boc-imines has been developed via C-H activation to afford a series of substituted 2-indolyl-methanamine derivatives with good functional group tolerance and regioselectivity. A wide range of indole-based alkylation products could be obtained in up to 95% yield.
创建时间:
2018-06-01



