cBioPortal for Cancer Genomics

cBioPortal是一个癌症基因组学数据库。最初由纪念斯隆凯特琳癌症中心开发，现由多机构团队维护，整合了包括TCGA、ICGC等在内的数百个癌症基因组研究数据。该数据库提供超过535个研究、约39.5万份样本的多维癌症基因组数据，涵盖泛癌研究、儿科癌症、免疫基因组学等多个主题，支持基因突变、拷贝数变异等分析功能。cBioPortal is a cancer genomics database. Originally developed by Memorial Sloan Kettering Cancer Center, it is now maintained by a multi-institutional team. It integrates hundreds of cancer genomics research datasets including TCGA, ICGC and other related resources, and provides multi-dimensional cancer genomics data from over 535 studies and approximately 395,000 samples. Covering multiple research themes such as pan-cancer research, pediatric cancer, immunogenomics and more, the database supports analytical functions including gene mutation analysis and copy number variation analysis.

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背景与挑战

背景概述

cBioPortal是一个由多机构维护的癌症基因组学数据库，整合了包括TCGA和ICGC在内的数百个研究，提供超过535项研究、约39.5万份样本的多维基因组数据。该数据库持续更新样本和功能，支持基因突变、拷贝数变异等分析，涵盖泛癌、儿科癌症等多个主题。