WP554 - ACE inhibitor pathway - Homo sapiens
收藏NIAID Data Ecosystem2026-05-02 收录
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https://www.ndexbio.org/viewer/networks/e173f276-5c64-11ec-b3be-0ac135e8bacf
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资源简介：
The core of this pathway was elucidated over a century ago and involves the conversion of angiotensinogen to angiotensin I (Ang I) by renin, its subsequent conversion to angiotensin II (Ang II) by angiotensin converting enzyme. Ang II activates the angiotensin II receptor type 1 to induce aldosterone synthesis, increasing water and salt resorption and potassium excretion in the kidney and increasing blood pressure.
Source: PharmGKB (https://www.pharmgkb.org/pathway/PA2023)
Proteins on this pathway have targeted assays available via the [CPTAC Assay Portal](https://assays.cancer.gov/available_assays?wp_id=WP554)
创建时间：
2025-04-17
