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Addition of Trifluoroborates to Oxetanyl <i>N</i>,<i>O</i>‑Acetals: Entry into Spiro and Fused Saturated Heterocycles

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NIAID Data Ecosystem2026-03-08 收录
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N,O-Acetals derived from 3-oxetanone and 1,2-amino alcohols undergo addition reactions with alkynyl-, allyl-, allenyl-, and vinylpotassium trifluoroborates. The resulting products undergo cyclization by orthogonal activation of the oxetane and the alkyne to give a diverse set of spiro and fused heterocycles.

创建时间:
2016-02-13
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