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Crystal structure of Lysine Specific Demethylase 1 (LSD1) with TAK-418 distomer, FAD-adduct

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Protein Data Bank Japan2023-11-29 更新2026-04-25 收录
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Crystal structure of Lysine Specific Demethylase 1 (LSD1) with TAK-418 distomer, FAD-adduct Descriptor: GLYCEROL, Lysine-specific histone demethylase 1A, MAGNESIUM ION, ... Authors: Oki, H. Deposit date: 2022-05-26 Release date: 2022-10-12 Last modified: 2023-11-29 Method: X-RAY DIFFRACTION (2.28 Å) Cite: Design, synthesis, and structure-activity relationship of TAK-418 and its derivatives as a novel series of LSD1 inhibitors with lowered risk of hematological side effects. Eur.J.Med.Chem., 239, 2022
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2022-05-26
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