Synthesis of Indeno[1,2‑c]furans via a Pd-Catalyzed Bicyclization of 2‑Alkynyliodobenzene and Propargylic Alcohol
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https://figshare.com/articles/dataset/Synthesis_of_Indeno_1_2_i_c_i_furans_via_a_Pd_Catalyzed_Bicyclization_of_2_Alkynyliodobenzene_and_Propargylic_Alcohol/2458021
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A general and efficient synthesis of indeno[1,2]furans via a Pd-catalyzed bicyclization reaction between 2-alkynyliodobenzenes and propargylic alcohols is described. The procedure furnishes indeno[1,2]furans with moderate to excellent yields (51%–78%) and a broad substrate scope. The cascade process combines the formation of one C–O bond and two C–C bonds in a single step.
创建时间:
2016-02-20



