PRS-PheWAS results for association of genetic risk of major depression with 23,004 outcomes in UK Biobank.

Genetic risk score was calculated as the weighted sum of all genome-wide significant risk alleles for major depression using full GWAS summary statistics as reported in Wray et al. 2019 and GWAS summary statistics excluding the UK Biobank and 23andMe sample from the mentioned study (noUKB). Estimates were generated by PHESANT. Results for continuous outcomes are the standard deviation change of inverse-rank normal transformed outcome per 1SD higher PRS.
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