five

Effects of LSD1 inhibitors on enhancer functions in T-ALL cells

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https://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE120314
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We treated the T-ALL cell line MOLT4 with a novel LSD inhibitor and performed ChIP-seq analysis using anti-histoneH3K27ac antibody to assess the enhancer function. We isolated fixed chromatin from MOLT4 cells treated with the LSD1 inhibitor S2157 and performed immunoprecipitation with anti-H3K27ac antibody, followed by deep sequencing.
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2019-02-21
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