Protection afforded by eVLP vaccines after 1 or 2 doses in cynomolgus macaques.
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Macaques were vaccinated with 3 mg of EBOV VLPs (total protein content) in 100ug of QS-21 at 6 week intervals with all challenges of ∼1000 pfu EBOV occurring 4 weeks after the final vaccination. Antibody responses were determined using an ELISA to detect IgGs against purified EBOV GPdTM or VP40 in sera drawn immediately prior to challenge. Protection afforded by eVLP vaccines after 1 or 2 doses in cynomolgus macaques.
创建时间：
2015-03-20
