LKB1 regulates adipose tissue ILC2 function through regulating mitochonrial
收藏NIAID Data Ecosystem2026-05-10 收录
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https://www.ncbi.nlm.nih.gov/sra/SRP358563
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资源简介：
Our study represents LKB1 defects lead to the loss and dysfunction of adipose tissue ILC2s.And we found that LKB1 regulate ILC2s homeostasis and cytokines function in a cell-intrinsic manner.In high-diet-fed mice,LKB1 in ILC2s protects against metabolic disturbances and fat fibrosis.LKB1 deficient in ILC2 impaired the oxidative phosphorylation and led to mitochondria loss though more mitophagy. Overall design: mRNA profiles of VAT ILC2s from 8-week old R5/+(WT) and R5/+Stk11f/f(KO) male mice
创建时间：
2025-09-18
