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Sequence-specific targeting of dosage compensation in Drosophila favors an active chromatin context

ChEBI2012-03-19 更新2026-07-21 收录

果蝇剂量补偿

染色质表观遗传调控

数据链接：

https://www.ebi.ac.uk/biostudies/ArrayExpress/studies/E-GEOD-34859 数据链接链接失效反馈

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Sequence-specific targeting of dosage compensation in Drosophila favors an active chromatin context

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创建时间：

2012-03-19

蛋白质-核酸复合物结构

染色质表观遗传调控

Crystal structure of the N-terminally acetylated BAH domain of Sir3 bound to the nucleosome core particle

NIAID Data Ecosystem60

Targeting of the dosage-compensated male X-chromosome during early Drosophila development. Targeting of the dosage-compensated male X-chromosome during early Drosophila development

果蝇剂量补偿

早期胚胎发育

The essential process of dosage compensation, which corrects for the imbalance in X-linked gene expression between XX females and XY males, represents a key model for how genes are targeted for coordi

NIAID Data Ecosystem40

Autoregulation of the Drosophila Noncoding roX1 RNA Gene

非编码RNA调控

果蝇剂量补偿

Most genes along the male single X chromosome in Drosophila are hypertranscribed about two-fold relative to each of the two female X chromosomes. This is accomplished by the MSL (male-specific lethal)

Figshare2016-01-18 更新30

HMGA2 interacts with KAT6A to regulate MMPs chromatin architecture and promote triple-negative breast cancer metastasis

癌症转移机制

染色质表观遗传调控

Triple-negative breast cancer (TNBC), the most lethal breast cancer subtype, demonstrates poor prognosis due to its high rates of metastasis, recurrence, and mortality. The metastatic potential in TNB

NIAID Data Ecosystem40

Induced Cdx2 binding in progenitor motor neurons and its effect on H3K27me3 chromatin domains [ChIP-Seq]

运动神经元发育

染色质表观遗传调控

We aim to understand the role that Cdx2 plays in specifying the rostro-caudal identity of differentiating motor neurons. We find that expressing Cdx2 in combination with FGF signaling is sufficient to

NIAID Data Ecosystem30

Sequence-specific targeting of dosage compensation in Drosophila favors an active chromatin context

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