DTI parameters including fractional anisotropy, axial diffusivity, radial diffusivity and mean diffusivity in the corpus callosum during the 8 week exposure period and following 8 weeks abstinence.

Fractional anisotropy (FA), axial diffusivity (DA, ×10−3 mm2/sec or ×10−6 mm2/sec*), radial diffusivity (DR, ×10−3 mm2/sec or ×10−6 mm2/sec*) and mean diffusivity (DM, ×10−3 mm2/sec or ×10−6 mm2/sec*). Data are expressed as mean of means (± SEM).†Effect of time from 0 to 8 weeks (two-way RM ANOVA with Holm–Sidak post-tests).*Note units at 16 weeks are different due to scans being performed ex vivo. CIT: chronic intermittent toluene.