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Additional file 9: of A pan-cancer analysis of driver gene mutations, DNA methylation and gene expressions reveals that chromatin remodeling is a major mechanism inducing global changes in cancer epigenomes

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Table S7. Chromatin regulators dysregulated by IDH1 and CIC in LGG. |Ti| is number of tumor types whose genome-wide methylation levels are significantly associated with the mutation status of CDG i; N1 is number of genome-wide genes whose expression levels are dysregulated by MDG i in all |Ti| tumor types; N2 is number of genes in list A that are dysregulated in all |Ti| tumor types; N3 is number of genes in list B that are dysregulated in all |Ti| tumor types; Enrichment PvalueA and PvalueB are calculated using hypergeometric distributions testing if genes in lists A and B occur more frequently than expected by random chance among genome-wide differentially expressed target genes. (XLSX 9 kb)

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2018-11-07
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