ER, mitochondria and ISR regulation by mt-HSP70 and ATF5 upon procollagen misfolding (E18.5 femur and tibia)
收藏Alliance of Genome Resources2026-08-01 收录
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We used single cell RNA sequencing (scRNA-seq) to identify femur and tibia osteoblast cell stress response pathway to misfolding of type I procollagen with Gly610->Cys substitution in the triple helical region of alpha2(I) chain. Femur and tibia cells were isolated from E18.5 embryos as described in Gorrell et al, Adv Sci, 2022
