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Crystal structure of EGFR 696-1022 T790M in complex with WZ4003

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Protein Data Bank Japan2024-03-27 更新2026-03-21 收录
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Crystal structure of EGFR 696-1022 T790M in complex with WZ4003 Descriptor: Epidermal growth factor receptor, N-{3-[(5-chloro-2-{[2-methoxy-4-(4-methylpiperazin-1-yl)phenyl]amino}pyrimidin-4-yl)oxy]phenyl}prop-2-enamide Authors: Zhu, S.J, Zhao, P, Yun, C.H. Deposit date: 2017-02-01 Release date: 2018-02-21 Last modified: 2024-03-27 Method: X-RAY DIFFRACTION (3.201 Å) Cite: Structural insights into drug development strategy targeting EGFR T790M/C797S. Oncotarget, 9, 2018

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2017-02-01
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