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Developmental trajectory of pre-hematopoietic stem cell formation from endothelium (scATAC-seq data set)

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https://www.ncbi.nlm.nih.gov/sra/SRP221063
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To examine the cell and molecular transitions between endothelial (E), hemogenic endothelial (HE), and intra-arterial clusters (IAC) cells, we profiled ~1700 cells from the caudal arteries (dorsal aorta, umbilical, vitelline) of embryonic day (E) 10.5 mouse embryos by single-cell ATAC sequencing (scATAC-Seq). We found extensive cis--regulatory landscape change during the endothelial to hematopoietic transition (EHT). Overall design: Single cell ATAC-seq profiles of cells involved in endothelial to hematopoietic transition (EHT) from mouse embryos at embryonic day 10.5
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2023-04-11
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