SARS-CoV-2 spike S2 trimer stabilized in the early fusion intermediate conformation (E-FICs-v3) bound to C77G12 (S2 local refinement)

SARS-CoV-2 spike S2 trimer stabilized in the early fusion intermediate conformation (E-FICs-v3) bound to C77G12 (S2 local refinement) Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, Spike protein S2 Authors: McCallum, M, Seattle Structural Genomics Center for Infectious Disease (SSGCID), Veesler, D. Deposit date: 2026-02-24 Release date: 2026-03-18 Last modified: 2026-05-27 Method: ELECTRON MICROSCOPY (2.7 Å) Cite: TMPRSS2-mediated coronavirus spike activation and inhibition. Nat.Struct.Mol.Biol., 33, 2026