Human dihydroorotate dehydrogenase in complex with a leflunomide derivative inhibitor 5
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Human dihydroorotate dehydrogenase in complex with a leflunomide derivative inhibitor 5 Descriptor: (2Z)-N-biphenyl-4-yl-2-cyano-3-cyclopropyl-3-hydroxyprop-2-enamide, Dihydroorotate dehydrogenase, FLAVIN MONONUCLEOTIDE, ... Authors: Davies, M, Heikkila, T, McConkey, G.A, Fishwick, C.W.G, Parsons, M.R, Johnson, A.P. Deposit date: 2009-01-29 Release date: 2009-06-09 Last modified: 2024-03-20 Method: X-RAY DIFFRACTION (1.8 Å) Cite: Structure-based design, synthesis, and characterization of inhibitors of human and Plasmodium falciparum dihydroorotate dehydrogenases J.Med.Chem., 52, 2009
创建时间:
2009-01-29



