Circulating Tumor Cells (CTCs) from metastatic breast cancer patients were harvested and grown in vitro for 30+ days in a novel short-term culture method. Additionally, RNA from the buffy coat of 5 he
To identify the downstream targets of macrophages that mediate tumor metastasis, we first established a highly metastatic cell line, named SCC7-M, then we performed proteomics analysis using the tumor
Cancer cells can disseminate from early-evolved primary lesions. It is thought that a state of early disseminated cancer cell (early DCC) dormancy would precede genetic maturation of DCCs and metastas
Purpose: Physical forces are prominent during tumor progression. However, it is still unclear how they impact and drive the diverse phenotypes found in cancer. Here, we investigate the impact of compr
