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PHF6 suppresses self-renewal of leukemic stem cells in AML. PHF6 suppresses self-renewal of leukemic stem cells in AML

NIAID Data Ecosystem2026-05-02 收录

干细胞自我更新

基因调控机制

数据链接：

https://www.ncbi.nlm.nih.gov/bioproject/PRJNA1128120 数据链接链接失效反馈

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资源简介：

This SuperSeries is composed of the SubSeries listed below. Overall design: Refer to individual Series

应用场景：

创建时间：

2024-06-25

微胶质细胞

干细胞自我更新

Microglia constitute a highly specialized network of tissue resident immune cells that is important for the control of tissue homeostasis and the resolution of virtually all diseases of the central ne

干细胞与再生医学数据中心2022-02-20 更新100

dCas9 Fusion to Computer Designed PRC2 Inhibitor Reveals Functional TATA Box in Distal Promoter Region [ChIP-seq]. dCas9 Fusion to Computer Designed PRC2 Inhibitor Reveals Functional TATA Box in Distal Promoter Region [ChIP-seq]

表观遗传学

基因调控机制

The critical process in development, bifurcation of cellular fates, requires epigenetic H3K27me3 marks propagated by PRC2 complex. However, the precise chromatin loci of functional H3K27me3 marks are

NIAID Data Ecosystem60

4C-seq protocol in mice macrophages

染色质构象

基因调控机制

A protocol for performing the 4C library and the analysis in mice macrophages. We used the ChIP-seq data to mark the DNA element regions (Silencer) and used the 4C-seq technique to investigate all the

NIAID Data Ecosystem50

Inferring gene regulatory logic from high-throughput measurements of thousands of systematically designed promoters. Saccharomyces cerevisiae

基因调控机制

启动子功能

Despite extensive research, our understanding of the rules according to which cis-regulatory sequences are converted into gene expression is limited We devised a method for obtaining parallel, highly

NIAID Data Ecosystem80

Expression profile of small nucleolar RNA (snoRNA) in acute myeloid leukemia.

急性髓系白血病snoRNA

干细胞自我更新

Leukemogenesis requires enhanced self-renewal activity, which is induced by specific oncogenes. The underlying molecular mechanisms remain incompletely understood. We transduced mouse lineage negative

NIAID Data Ecosystem60

PHF6 suppresses self-renewal of leukemic stem cells in AML. PHF6 suppresses self-renewal of leukemic stem cells in AML

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