Jarid2 methylation is required for PRC2 functioning during ES cells differentiation

ChEBI2015-01-22 更新2026-07-21 收录

表观遗传调控

干细胞分化

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https://www.ebi.ac.uk/biostudies/ArrayExpress/studies/E-GEOD-55630 数据链接链接失效反馈

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Jarid2 methylation is required for PRC2 functioning during ES cells differentiation

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2015-01-22

DNA-RNA Immunoprecipitation sequencing (DRIP-seq) of human NT2 cells

R-loop研究

表观遗传调控

Strand asymmetry in the distribution of guanines and cytosines, measured by GC skew, predisposes DNA sequences towards R-loop formation upon transcription. Previous work revealed that GC skew and R-lo

NIAID Data Ecosystem20

DNMT3A Reads and Connects Histone H3K36me2 to DNA methylation [RNA-seq]

表观遗传调控

甲基化反应机制

DNA methylation at the 5-position of cytosine (5mC) is a crucial epigenetic mark in regulating biological processes including gene silencing, gene imprinting, and X chromosome inactivation. It has lon

NIAID Data Ecosystem00

Stage-specific Kdm6b-transcription factor partnerships orchestrate temporal precision during stepwise motor neuron differentiation [RNA-seq]

运动神经元

表观遗传调控

Histone modifiers instruct cellular differentiation, yet how they achieve temporal precision remains enigmatic. Here we demonstrate that the H3K27 demethylase Kdm6b acts as a master epigenetic conduct

NIAID Data Ecosystem00

DNA dioxygenases Tet2/3 control epithelial differentiation [RNA-seq]

毛囊上皮分化

表观遗传调控

Execution of lineage-specific differentiation programs requires tight coordination between many regulators including Ten-eleven translocation (TET) family enzymes catalyzing 5-methylcytosine oxidation

Alliance of Genome Resources00

Genome-wide analysis of histone H3 acetylation levels of wild type, hda6, hdc1, and hda19 in short day conditions [ChIP-seq]

组蛋白H3乙酰化修饰

表观遗传调控

To investigate whether the expression of upregulated genes in hdc1 and hda19 is assoiated with histone acetylation levels increased in the hdc1 and hda19 mutants, We carried out ChIP-seq to examine hi

NIAID Data Ecosystem00

Jarid2 methylation is required for PRC2 functioning during ES cells differentiation

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