Original data of the article entitled “YB-1 recruits Drosha to promote splicing of pri-miR-192 to mediate the proangiogenic effects of H2S.” Zhou Y et al

miR-192 has a central role for the cells to sense the proangiogenic signals of H2S. The study reveals a new mechanism to regulate microRNA biosynthesis at the primary-to-precursor step in sensing H2S. In addition to H2S donors, the study provides some new potential targets deserves to be explored for anti-ischemia therapies, e.g., approaches based on regulating CSE and miR-192
The file named Zhou Y et al miRNAarray data 20200514 includes the microarray profiling of microRNAs showed a preliminary pattern of changes in the vascular endothelial cells treated with H2S.
The file named Zhou Y et al Western Blot data 20200514 includes unedited images for all blots shown in the manuscript.

miR-192在细胞感知硫化氢促血管生成信号中扮演着核心角色。研究揭示了在感知硫化氢过程中，对微RNA生物合成进行调控的新机制，该机制作用于初级转录物至前体步骤。除了硫化氢供体之外，研究还提供了一些具有探索潜力的新靶点，这些靶点对于抗缺血治疗具有重要意义，例如基于调节CSE和miR-192的疗法。名为“Zhou Y等miRNAarray数据20200514”的文件包含了处理硫化氢的血管内皮细胞微阵列分析，显示了初步的变化模式。而名为“Zhou Y等Western Blot数据20200514”的文件则包含了论文中所有印迹的未编辑图像。